What are the guidelines for use of urinary tumor markers in the diagnosis of bladder cancer?

Updated: Feb 23, 2021
  • Author: Kara N Babaian, MD, FACS; Chief Editor: Bradley Fields Schwartz, DO, FACS  more...
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The EAU guidelines on non–muscle-invasive bladder cancer state that most of these tests are more sensitive than cytology but are less specific, and none have been accepted for diagnosis or follow-up in routine urologic practice or in guidelines. [69]  NCCN guidelines generally agree with the EAU guidelines but note that urinary biomarker tests approved by the FDA may be considered for use in monitoring for recurrence; however, this is a category 2B recommendation (ie, based on lower-level evidence). [1]

See Urine Tumor Markers in Bladder Cancer Diagnosis for more information on this topic.

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