How does the WHO classify bladder cancers?

Updated: Feb 23, 2021
  • Author: Kara N Babaian, MD, FACS; Chief Editor: Bradley Fields Schwartz, DO, FACS  more...
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Answer

The current WHO/International Society of Urological Pathology (ISUP) system classifies bladder cancers as low grade or high grade. [5] Tumors are also classified by growth patterns: papillary (70%), sessile or mixed (20%), and nodular (10%). (See the images below.)

Bladder cancer. Papillary bladder tumors such as t Bladder cancer. Papillary bladder tumors such as this one are typically of low stage and grade (Ta-G1). Courtesy of Abbott and Vysis Inc.
Bladder cancer. Sessile lesions as shown usually i Bladder cancer. Sessile lesions as shown usually invade muscle, although occasionally a tumor is detected at the T1-G3 stage prior to muscle invasion. Courtesy of Abbott and Vysis Inc.

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