Are pumpkin seeds (Cucurbita pepo) an effective treatment for benign prostatic hyperplasia (BPH)?

Updated: Jan 15, 2019
  • Author: Levi A Deters, MD; Chief Editor: Edward David Kim, MD, FACS  more...
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Answer

Observational studies, retrospective surveys, and randomized controlled trials have provided evidence that pumpkin seeds may reduce urinary urgency and frequency in men with LUTS related to BPH. Adverse effects are mild. Suggested mechanisms of action include increased prostaglandin synthesis, due to their high amounts of linoleic acid, and anti-inflammatory effects from gamma-tocopherol and nitric acid precursors. [37]


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