What are the recommendations for prostate cancer screening in patients with benign prostatic hyperplasia (BPH)?

Updated: Feb 19, 2021
  • Author: Levi A Deters, MD; Chief Editor: Edward David Kim, MD, FACS  more...
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The ACS recommends that men receive information about the uncertainties, risks, and potential benefits associated with prostate cancer screening. After this discussion, if the patient wishes to proceed with screening (ie, prostate-specific antigen [PSA] testing and digital rectal examination [DRE] for prostate cancer), the ACS recommends that screening start at the following ages:

  • Age 50 years in men at average risk for prostate cancer who are expected to live at least 10 more years

  • Age 45 years in men at high risk for prostate cancer (African Americans and men with a first-degree relative diagnosed with prostate cancer before age 65)

  • Age 40 years in men at very high risk (those with more than one first-degree relative who had prostate cancer at an early age).

A physician should discuss the risks and benefits of PSA screening with the patient. Notably, men with larger prostates may have slightly higher PSA levels.

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