Which medications in the drug class Alpha Blockers, Antihypertensives are used in the treatment of Nephrolithiasis?

Updated: Jun 21, 2018
  • Author: Chirag N Dave, MD; Chief Editor: Bradley Fields Schwartz, DO, FACS  more...
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Answer

Alpha Blockers, Antihypertensives

Alpha-blockers are smooth-muscle relaxants. They have been shown to facilitate ureteral stone passage.

Tamsulosin (Flomax)

Tamsulosin, an alpha-1 selective blocker, is indicated for the treatment of lower urinary tract symptoms due to prostatic enlargement. An off-label use, as discussed above, is to facilitate passage of ureteral stones. Only short-term therapy (10 d) should be considered for this indication.

Terazosin

Terazosin is indicated for the treatment of hypertension, as well as lower urinary tract symptoms due to prostatic enlargement. An off-label use is to facilitate passage of ureteral stones. Only short-term therapy (10 d) should be considered for this indication.


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