Which medications in the drug class Xanthine Oxidase Inhibitors are used in the treatment of Nephrolithiasis?

Updated: Jun 21, 2018
  • Author: Chirag N Dave, MD; Chief Editor: Bradley Fields Schwartz, DO, FACS  more...
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Answer

Xanthine Oxidase Inhibitors

Uricosuric agents help prevent nephropathy. They also help prevent recurrent calcium oxalate calculi.

Allopurinol (Zyloprim, Aloprim)

Allopurinol inhibits xanthine oxidase, the enzyme that synthesizes uric acid from hypoxanthine. It reduces the synthesis of uric acid without disrupting the biosynthesis of vital purines.


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