Which organ systems are directly affected by premature ejaculation (PE)?

Updated: Jan 15, 2019
  • Author: Samuel G Deem, DO; Chief Editor: Edward David Kim, MD, FACS  more...
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Premature ejaculation is believed to be a psychological problem and does not represent any known organic disease involving the male reproductive tract or any known lesions in the brain or nervous system. The organ systems directly affected by premature ejaculation include the following [4] :

  • Male reproductive tract (ie, penis, prostate, seminal vesicles, testicles, and their appendages)

  • Portions of the central and peripheral nervous system controlling the male reproductive tract

  • Reproductive organ systems of the sexual partner (if female) that may not be stimulated sufficiently to achieve orgasm [5]

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