What is the initial evaluation and treatment of toxic epidermal necrolysis in burn patients?

Updated: Jan 10, 2018
  • Author: Robert L Sheridan, MD; Chief Editor: John Geibel, MD, DSc, MSc, AGAF  more...
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Answer

Answer

Toxic epidermal necrolysis is a systemic process triggered by a medication or viral syndrome that results in a separation at the dermal-epidermal junction. Both a cutaneous wound and a visceral wound develop, with variable degrees of dermal, mucosal, and conjunctival involvement. Endotracheal intubation is often required for airway protection. Wound care should be directed to prevent desiccation and superinfection, and nutritional support is important.


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