What is autologous (acute) normovolemic hemodilution?

Updated: Apr 16, 2019
  • Author: Linda L Maerz, MD, FACS, FCCM; Chief Editor: Emmanuel C Besa, MD  more...
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This technique involves collecting a patient’s blood (2-4 units) into anticoagulant-containing storage bags at the outset of surgery, accompanied by intravenous replacement with crystalloids or colloids to maintain normovolemia. The patient’s whole blood can then be transfused later in the case as needed. The evidence on the overall efficacy of autologous normovolemic hemodilution is conflicting with respect to blood savings and transfusion avoidance, but it appears to be safe and efficacious in centers that make routine use of this technique. [65, 66]

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