What is the increased risk for cancer following lung transplantation?

Updated: Aug 19, 2019
  • Author: Bryan A Whitson, MD, PhD; Chief Editor: Mary C Mancini, MD, PhD, MMM  more...
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Answer

Patients who have undergone solid organ transplantation are at increased risk for infection-related and unrelated cancers due to immunosuppression and oncogenic viral infections.

In a large cohort study that used data from the US Scientific Registry of Transplant Recipients and 13 state and regional cancer registries, overall cancer risk was elevated with an incidence of 1375 per 100,000 person-years. [60] Lung cancer risk was most elevated in lung recipients. Non-Hodgkin lymphoma and cancers of the lung, liver, and kidney were also reported as common malignancies in organ transplant patients.


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