What is the role of antilymphocyte antibody preparations in lung transplantation?

Updated: Aug 19, 2019
  • Author: Bryan A Whitson, MD, PhD; Chief Editor: Mary C Mancini, MD, PhD, MMM  more...
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Answer

Antilymphocyte antibody preparations, the so-called cytolytic therapies, have been used in patients undergoing clinical lung transplantation. These preparations include antilymphocyte globulin, antithymocyte globulin, a murine monoclonal antibody to the CD3 complex of human lymphocyte (OKT3) and an anti-IL-2R antagonist antibody preparation. The use of these agents generally is for induction therapy. [3]


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