What is the role of rapamycin in lung transplantation?

Updated: Aug 19, 2019
  • Author: Bryan A Whitson, MD, PhD; Chief Editor: Mary C Mancini, MD, PhD, MMM  more...
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Answer

Rapamycin is the newest immunosuppressive agent to be introduced. Its mode of action is less well understood but has antilymphoproliferative activity. [48] Due to its antihealing properties, it is not usually used immediately posttransplant but rather when chronic rejection or bronchiolitis obliterans syndrome becomes evident. It is also associated with renal toxicity and pneumonitis.


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