What are the relative contraindications for lung transplantation?

Updated: Aug 19, 2019
  • Author: Bryan A Whitson, MD, PhD; Chief Editor: Mary C Mancini, MD, PhD, MMM  more...
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Answer

Adults older than 75 years are unlikely to be candidates for lung transplantation in most cases. Although age by itself should not be considered a contraindication to transplant, increasing age generally is associated with comorbid conditions that are either absolute or relative contraindications.

Relative contraindications include the following [16] :

  • Older age
  • Class I obesity (BMI 30.0–34.9 kg/m 2)
  • Progressive or severe malnutrition
  • Severe, symptomatic osteoporosis
  • Prior chest surgery with lung resection
  • Infection with highly resistant or virulent bacteria, fungi, and certain strains of mycobacteria (eg, chronic extrapulmonary infection expected to worsen after transplantation)

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