What causes lymphatic tumors in the mediastinum?

Updated: Feb 16, 2021
  • Author: Mary C Mancini, MD, PhD, MMM; Chief Editor: John Geibel, MD, MSc, DSc, AGAF  more...
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Several types of lymphomas can be found in the mediastinum. [2, 3] They may be found in the mediastinum as a primary process or as one of a number of involved locations in a systemic process. All forms of lymphoma originate from abnormalities of specific types of lymphocytes. They are generally divided into Hodgkin and non-Hodgkin lymphomas.

The many forms of non-Hodgkin lymphoma are categorized by cell type. [4, 5] The most common types of lymphoma found in the mediastinum include immunoblastic T-cell, immunoblastic B-cell, follicular center cell, and lymphoblastic. [6] The most common form of Hodgkin lymphoma found in the mediastinum is the nodular sclerosing type. So-called mediastinal gray-zone lymphomas occur but are rare. [7, 8]

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