What is the role of gene expression in the workup of secondary lung tumors?

Updated: Feb 08, 2019
  • Author: Daniel S Schwartz, MD, MBA, FACS; Chief Editor: John Geibel, MD, DSc, MSc, AGAF  more...
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Answer

In the remaining patients who have not been otherwise diagnosed, further classification based on gene expression may be expected to provide additional classifying information. [27, 28, 29]

The other approach would be a rather simultaneous method in which the gene expression profile is determined up front. Complete replacement of histologic and immunohistochemical evaluation by these methods has been suggested. Both strategies may have pros and cons in terms of accuracy, time frames, and costs. 


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