What is the role of genetics in the etiology of thoracic aortic aneurysm (TAA)?

Updated: Apr 02, 2021
  • Author: Elaine Tseng, MD; Chief Editor: Mary C Mancini, MD, PhD, MMM  more...
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Answer

Authorities strongly agree that genetics play a role in the formation of aortic aneurysms. [13] Of first-degree relatives of patients with aortic aneurysms, 15% have an aneurysm. This appears especially true in first-degree relatives of female patients with aortic aneurysms. Thus, inherited disorders of connective tissue appear to contribute to the formation of aortic aneurysms.


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