How is sickle cell disease (SCD) treated?

Updated: Jul 24, 2019
  • Author: Ivan Ramirez, MD; Chief Editor: Felix S Chew, MD, MBA, MEd  more...
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Answer

Interventional radiologists may play a role in obtaining a sample to identify the infecting organism in osteomyelitis. Also, patients with subperiosteal and soft tissue abscesses may benefit from imaging guided drainage with light sedation, avoiding surgery and general anesthesia.

There are no approved drugs for children with sickle cell disease, but hydroxyurea is approved for the treatment of sickle cell disease in adults. In a meta-analysis, Strouse et al studied the efficacy, effectiveness, and toxicity of hydroxyurea in children with sickle cell disease. The investigators found that hemoglobin levels increased from 5-10% to 15-20%; hemoglobin concentration increased modestly (approximately 1 g/L) but significantly; hospitalizations decreased by 56-87%; and the frequency of pain crisis decreased. [22]


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