Which nuclear imaging findings are characteristic of congenital lobar emphysema (CLE)?

Updated: Apr 08, 2019
  • Author: Beverly P Wood, MD, MSEd, PhD; Chief Editor: John Karani, MBBS, FRCR  more...
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Ventilation-perfusion scanning demonstrates characteristic results (see the image below).

Perfusion scan in right posterior oblique (RPO) pr Perfusion scan in right posterior oblique (RPO) projection shows virtually no perfusion of the right middle lobe.

Ventilation is initially diminished in the affected lobe, but ultimately, isotope retention is seen because of delayed emptying of alveoli in the emphysematous lobe. The markedly attenuated vascularity of the involved lobe results in decreased perfusion of the enlarged lobe.

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