What are the USPSTF guidelines for ovarian cancer screening?

Updated: Feb 27, 2019
  • Author: Arthur C Fleischer, MD; Chief Editor: Eugene C Lin, MD  more...
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Answer

Answer

U.S. Preventive Services Task Force (USPSTF)

The U.S. Preventive Services Task Force (USPSTF) has concluded that annual screening of asymptomatic women with transvaginal ultrasonography and testing for a serum tumor marker, cancer antigen (CA)–125, does not reduce ovarian cancer deaths, but can lead to major surgical interventions in women who do not have cancer. With the harms of screening outweighing the benefits, USPSTF recommends against routine screening. [15]

The consensus among major medical organizations is in agreement with the USPSTF that screening for ovarian cancer in the general population is not recommended. However, the American College of Obstetricians and Gynecologists (ACOG) and the Society of Gynecologic Oncologists (SGO) recommend that women at high risk be offered an evaluation includes transvaginal ultrasonography, CA-125 testing, and a thorough pelvic examination. [16]


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