Which conditions are included in the differential diagnoses of hemophilia?

Updated: Sep 27, 2019
  • Author: Lars J Grimm, MD, MHS; Chief Editor: Felix S Chew, MD, MBA, MEd  more...
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Conditions in the differential diagnosis include ankle fractures, femoral head avascular necrosis, elbow trauma, juvenile rheumatoid arthritis, and pigmented villonodular synovitis. Trauma, scurvy, myeloproliferative disease, and anticoagulant overdose may cause acute hemarthrosis. Over time, juvenile rheumatoid arthritis causes joint deformities in a pattern that is similar to that of hemophilia, and pigmented villonodular synovitis produces hemosiderin deposition in the synovium similar to that of hemophilia. In addition, synovial hemangiomas may look like hemorrhagic synovitis. [18]

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