What are limitations of imaging in the workup of hemophilia?

Updated: Sep 27, 2019
  • Author: Lars J Grimm, MD, MHS; Chief Editor: Felix S Chew, MD, MBA, MEd  more...
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As mentioned above, plain radiographs cannot clearly depict soft-tissue changes. In early hemophilic disease, radiographs may not be needed at all. MRI is the best technique for detecting soft-tissue changes, but it is expensive, and 10% of patients are too claustrophobic to undergo the examination. In addition, some patients' implanted devices, such as pacemakers, preclude MRI evaluation. MRI may not be warranted when the radiographic findings already show advanced disease.

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