What are the Trans-Atlantic Retroperitoneal Sarcoma Working Group imaging guidelines for pleomorphic sarcoma (malignant fibrous histiocytoma) of soft tissue?

Updated: Nov 07, 2018
  • Author: Gregory Scott Stacy, MD; Chief Editor: Felix S Chew, MD, MBA, MEd  more...
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The Trans-Atlantic Retroperitoneal Sarcoma Working Group was established to address challenging management issues encountered when caring for patients with retroperitoneal soft tissue sarcomas (RPS). Their imaging recommendations include the following [7] :

  • Review of cross-sectional imaging by a dedicated tumor board is required.
  • CT of the chest, abdomen, and pelvis with intravenous contrast is the preferred imaging modality. MRI may be a useful ancillary modality in selected cases to define extent of adjacent organ/structure involvement that is not clear on CT but is not required in most cases.
  • MRI is an option for patients with contrast allergy, for pelvic tumors, or for cases in which detailed anatomic information (eg, sciatic foramen) is required.
  • PET scan is rarely indicated; it may be indicated if the extent of active abdominal disease is difficult to evaluate and/or if there is uncertainty about different growth characteristics in multifocal lesions that would alter management

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