What is the accuracy of CT scanning for transitional cell carcinomas (TCCs) imaging?

Updated: Mar 18, 2019
  • Author: Ali Nawaz Khan, MBBS, FRCS, FRCP, FRCR; Chief Editor: Eugene C Lin, MD  more...
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CT is of limited value in staging low-grade disease because it cannot accurately depict the depths of tumoral invasion. Therefore, stages Ta-T2 cannot be distinguished. The strength of CT lies in the staging of high-grade disease, because of its ability to demonstrate peripelvic, periureteric, and local pelvic extensions, as well as distant metastases.

Inevitably, studies differ with regard to the sensitivity and specificity of preoperative CT scanning in the detection and accurate staging of TCC. The reported range for detection efficiency is 86-100%. The results of most studies suggest a range of 55-64% for correct TNM staging, compared with surgical findings.

Understaging appears to be a limiting factor. However, results with newer scanners and adjunct techniques such as virtual cystoscopy and postmicturition scanning should improve the overall accuracy of staging with CT.

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