Which retrograde pyelography findings are characteristic of transitional cell carcinomas (TCCs)?

Updated: Mar 18, 2019
  • Author: Ali Nawaz Khan, MBBS, FRCS, FRCP, FRCR; Chief Editor: Eugene C Lin, MD  more...
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Retrograde pyelography in ureteric TCC may show focal expansion of ureters around and distal to the mass; such a finding is called the champagne, or goblet, sign. This finding is helpful in differentiating TCC from focal lesions of other causes, such as calculi or blood clots. Typically, calculi and blood clots do not demonstrate a goblet sign because they do not progressively stretch the ureteral wall from slow growth. Occasionally, the catheter coils below the mass during retrograde catheterization; this is called the Bergman sign. (See the image below.)

Left retrograde pyelogram shows marked irregularit Left retrograde pyelogram shows marked irregularity of the infundibulum of the upper pole calyx caused by infiltration by transitional cell carcinoma. This information was unavailable on the CT scans.

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