What are transitional cell carcinomas (TCCs)?

Updated: Mar 18, 2019
  • Author: Ali Nawaz Khan, MBBS, FRCS, FRCP, FRCR; Chief Editor: Eugene C Lin, MD  more...
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Embryologic derivation of the collecting system of the urinary tract occurs from the fetal mesonephros. As a result of this development, tumors of the renal collecting system have cell origins different from those of the renal parenchyma. These tumors are classified on the basis of their respective mesodermal or epithelial tissue origin. Primary neoplasms of the renal collecting system represent 10% of renal tumors, of which approximately 80% are malignant. Most are transitional cell carcinomas (TCCs).

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