What is the prevalence and cause of portal vein (PV) complication following whole-liver orthotopic liver transplantation (OLTX)?

Updated: Mar 01, 2019
  • Author: Fazal Hussain, MD, MPH; Chief Editor: John Karani, MBBS, FRCR  more...
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Answer

Answer

Complications involving the PV occur in approximately 1-13% of OLTX recipients. Portal vein stenosis (PVS) usually occurs at the donor-recipient anastomosis (see the images below). Portal vein thrombosis (PVT) often involves the main extrahepatic segment (see the images below). Causes of PVS and PVT include surgical difficulties, thrombus formation from the portal venous bypass cannula, excessive vessel redundancy, and hypercoagulability. PVS can lead to PVT. PVT and hemodynamically significant PVS cause graft dysfunction and portal hypertension.


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