How is Crohn disease differentiated from ulcerative colitis (UC) on imaging?

Updated: Apr 23, 2019
  • Author: Ali Nawaz Khan, MBBS, FRCS, FRCP, FRCR; Chief Editor: Eugene C Lin, MD  more...
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Crohn disease is important in the differential diagnosis of ulcerative colitis, though it is not always possible to differentiate these 2 conditions on the basis of imaging.

Hansmann and associates evaluated the diagnostic role of hydro-MRI in 33 patients suspected of having either Crohn disease or ulcerative colitis and concluded that hydro-MRI was a reliable modality for diagnosing Crohn disease. [26] A correct diagnosis was made with MRI in all 24 patients with active Crohn disease. However, MRI results were positive in only 2 of 5 patients with ulcerative colitis. In 5 patients, IBD was excluded. No false-positive results occurred.

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