What is carcinoma of the gallbladder?

Updated: Apr 12, 2018
  • Author: Gregory M Szarnecki, MD; Chief Editor: John Karani, MBBS, FRCR  more...
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Although uncommon, carcinoma of the gallbladder (GB) is the most common primary hepatobiliary carcinoma, is the fifth most common malignancy of the gastrointestinal (GI) tract, and predominantly affects older persons with long-standing cholecystolithiasis. GB epithelial tumors tend to behave similarly to other GI adenocarcinomas. When the diagnosis is made incidentally at the time of cholecystectomy, surgical resection can be curative [1, 2, 3] ; however, more commonly, the tumor is unresectable and rarely diagnosed preoperatively despite patients' symptoms. Early diagnosis can improve the clinical outcome and cure rate of GB carcinoma.

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