What is the role of thallium-201 (201Tl) scans in thoracic non-Hodgkin lymphoma (NHL) imaging?

Updated: Mar 05, 2019
  • Author: Ali Nawaz Khan, MBBS, FRCS, FRCP, FRCR; Chief Editor: Eugene C Lin, MD  more...
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Thallium-201 (201Tl) is of interest in differentiating cerebral lymphomas from infectious lesions in AIDS patients, but it is less useful in extracerebral lymphomas. Tl-201 has a higher avidity for low-grade NHL than does 67Ga; it therefore has a complementary role to 67Ga in the diagnosis of low-grade NHL. However, the sensitivity of 201Tl for high-grade NHL is generally poor; in this case, 67Ga scanning is the preferred imaging technique.

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