What is the role of indium-111 (111In) octreotide and pentetreotide scans in thoracic non-Hodgkin lymphoma (NHL) imaging?

Updated: Mar 05, 2019
  • Author: Ali Nawaz Khan, MBBS, FRCS, FRCP, FRCR; Chief Editor: Eugene C Lin, MD  more...
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Answer

Answer

Indium-111 (111In) octreotide and pentetreotide scans may differentiate lymphomas and other mediastinal masses from mediastinal carcinoids. Carcinoids, including other neuroendocrine tumors, have somatostatin receptors and therefore can be imaged with somatostatin analogues (octreotide, pentetreotide) tagged to an appropriate radioisotope. Single-photon emission CT (SPECT) scanning and subtraction techniques improve detection.


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