What is the role of image-guided biopsy in the diagnosis of thoracic non-Hodgkin lymphoma (NHL)?

Updated: Mar 05, 2019
  • Author: Ali Nawaz Khan, MBBS, FRCS, FRCP, FRCR; Chief Editor: Eugene C Lin, MD  more...
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Answer

Answer

Image-guided biopsy (with US, conventional radiography, or CT scanning) conducted using fine-needle aspiration (FNA) or core-needle techniques is considered safe and is increasingly used in preference to a surgical biopsy. Interpretation of FNA results needs an expert cytopathologic opinion. Differentiation of various types of mediastinal tumors, such as thymomas, lymphomas, and germ cell tumors, is possible when core-needle biopsy material is subjected to special histologic staining, including immunohistochemical techniques.


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