What are the signs and symptoms of pulmonary Kaposi sarcoma (KS)?

Updated: Mar 13, 2019
  • Author: Ali Nawaz Khan, MBBS, FRCS, FRCP, FRCR; Chief Editor: Eugene C Lin, MD  more...
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Answer

Answer

Usually, mucocutaneous lesions are the first clinical sign of KS. Lesions usually measure 1-2 cm in diameter and are raised, violaceous, and plaquelike. They may appear brown or black in patients with dark skin. Lesions increase in size and number as the disease progresses. Involvement of the GI tract, lymph nodes, lungs, and other viscera is common. Pulmonary involvement occurs in one third of patients and is recognized clinically in 10-15% of patients. Symptoms of KS, such as breathlessness, cough, fever, and wheezing, are nonspecific. Hemoptysis may occur but is unusual. Although lung involvement invariably follows mucocutaneous disease, this may not be clinically apparent. [10] Pulmonary KS with bone metastases as the first presentation in HIV patients without the involvement of visceral organs or associated skin lesion has been reported. [11]


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