What is the role of radiopharmaceuticals in the imaging of myocardial ischemia?

Updated: Aug 07, 2019
  • Author: Thomas F Heston, MD, FAAFP, FASNC, FACNM; Chief Editor: Eugene C Lin, MD  more...
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Answer

Radiopharmaceuticals in use include thallium-201, palmitate, and rubidium-82. Iodinated fatty acids based on iodine-123 include iodohexadecanoic acid and iodophenylpentadecanoic acid. These are newer agents used to image myocardial energy metabolism. [25, 29, 44, 12, 13, 14] . Technetium-99m-sestamibi and Tc-99m-tetrofosmin are commercial radiopharmaceuticals for MPI by SPECT. Basic pathophysiology of ischemic heart disease has been improved by the application of F-18 fluorodeoxyglucose (FDG) and F-18 sodium fluoride (NaF). [8]


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