Which medications in the drug class Corticosteroids are used in the treatment of Polymyositis?

Updated: Feb 12, 2018
  • Author: Mythili Seetharaman, MD; Chief Editor: Herbert S Diamond, MD  more...
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Answer

Corticosteroids

These agents inhibit the inflammatory process via multiple mechanisms, including the inhibition of proinflammatory cytokine production, monocyte/macrophage function, and angiogenesis.

Prednisone

Prednisone is an anti-inflammatory and immunosuppressive agent used in the treatment of autoimmune disorders. It may decrease inflammation by reversing increased capillary permeability and suppressing neutrophilic activity. Prednisone also stabilizes the lysosomal membrane and suppresses lymphocytes, reducing cytokine and antibody production.

Corticotropin (Acthar Gel, HP Acthar Gel)

Porcine ACTH, stimulates adrenocortical hormone production


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