Which medications in the drug class DMARDs, TNF Inhibitors are used in the treatment of Polymyositis?

Updated: Jun 13, 2020
  • Author: Mythili Seetharaman, MD; Chief Editor: Herbert S Diamond, MD  more...
  • Print
Answer

DMARDs, TNF Inhibitors

These agents may be used in refractory cases of polymyositis that have failed to respond to conventional therapy with steroids.

Etanercept (Enbrel)

Etanercept binds specifically to TNF and blocks its interaction with cell-surface TNF receptors, rendering TNF biologically inactive.

Infliximab (Remicade)

Infliximab binds to soluble and transmembranous forms of TNF-alpha, rendering TNF biologically inactive.


Did this answer your question?
Additional feedback? (Optional)
Thank you for your feedback!