Which malignancies are more common in patients with polymyositis?

Updated: Jan 05, 2021
  • Author: Mythili Seetharaman, MD; Chief Editor: Herbert S Diamond, MD  more...
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Answer

The incidence of lung, bladder, and non-Hodgkin lymphoma may be increased in patients with polymyositis, especially in the first year after diagnosis. Nicoletis et al reported that a high pretreatment neutrophil-to-lymphocyte ratio (≥5.5) is associated with an increased risk of cancer in patients with polymyositis/dermatomyositis. These authors concluded that in patients age 60 years and older, a high neutrophil-to-lymphocyte ratio should prompt investigation for cancer, both at diagnosis of polymyositis and during follow-up. [16]

 


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