How are polymyositis and inclusion body myositis differentiated?

Updated: Jan 05, 2021
  • Author: Mythili Seetharaman, MD; Chief Editor: Herbert S Diamond, MD  more...
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Although classified as an inflammatory myopathy, inclusion body myositis shows minimal evidence of inflammation. This is the most common inflammatory myopathy in patients older than age 50 years. It more commonly presents as asymmetrical, distal weakness and also has distinct biopsy findings. Studies so far have yielded less favorable results than treatment for polymyositis and dermatomyositis. (See Treatment and Medication.)

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