What is the role of lab tests in the workup of mixed connective-tissue disorder (MCTD)?

Updated: Oct 01, 2018
  • Author: Eric L Greidinger, MD; Chief Editor: Herbert S Diamond, MD  more...
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Laboratory studies used in the workup for mixed connective-tissue disorder (MCTD) are as follows:

  • Complete blood cell count (CBC)
  • Urinalysis
  • Routine blood chemistry
  • Muscle enzymes if myositis is suspected clinically
  • Antinuclear antibodies
  • Anti–U1-ribonucleoprotein (RNP) antibodies
  • Amylase and lipase - To assess for pancreatitis if clinically indicated

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