Which medications in the drug class Immunoglobulin agents are used in the treatment of Viral Arthritis?

Updated: Nov 12, 2019
  • Author: Rabea Ahmed Khouqeer, MD, FRCPC, FAAAAI; Chief Editor: Herbert S Diamond, MD  more...
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Answer

Immunoglobulin agents

Immunoglobulins are used to improve clinical and immunologic aspects of the disease. They may decrease autoantibody production and increase solubilization and removal of immune complexes.

Immune globulin, intravenous (Carimune NF, Gammaplex, Octagam, Gammagard)

Neutralizes circulating myelin antibodies through antiidiotypic antibodies; down-regulates proinflammatory cytokines, including INF-gamma; blocks Fc receptors on macrophages; suppresses inducer T and B cells and augments suppressor T cells; blocks complement cascade; promotes remyelination; may increase CSF IgG (10%).Immune globulin, intravenous (Carimune NF, Gammaplex, Octagam, Gammagard)

Intravenous immune globulin (IVIg) neutralizes circulating myelin antibodies through anti-idiotypic antibodies; down-regulates proinflammatory cytokines, including interferon gamma; blocks Fc receptors on macrophages; suppresses inducer T and B cells while augmenting suppressor T cells; blocks the complement cascade; promotes remyelination; and may increase immunoglobulin G (IgG) in cerebrospinal fluid (CSF) (10%).


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