How is HIV-caused viral arthritis treated?

Updated: Nov 12, 2019
  • Author: Rabea Ahmed Khouqeer, MD, FRCPC, FAAAAI; Chief Editor: Herbert S Diamond, MD  more...
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For cases involving HIV infection, use currently recommended antiretroviral regimens, and treat symptoms with analgesics and NSAIDs. Administer sulfasalazine and methotrexate to patients who have conditions refractory to NSAID therapy. Prednisone, antimalarials, and other agents have been used successfully in patients with polymyositis, reactive arthritis, Sjögrenlike syndrome, psoriatic arthritis, and vasculitis.

Antiretroviral and prophylactic therapy, trimethoprim-sulfamethoxazole, and pentamidine help improve associated rheumatic symptoms. Intravenous immune globulin (IVIg), interleukin (IL)–12, IL-2, interferon gamma, or sargramostim may be effective in some HIV-infected patients with arthritis.

For human T-lymphotropic virus–1 (HTLV-1) infection, current treatment options are poor.

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