Which physical findings are characteristic of HBV-caused viral arthritis?

Updated: Nov 12, 2019
  • Author: Rabea Ahmed Khouqeer, MD, FRCPC, FAAAAI; Chief Editor: Herbert S Diamond, MD  more...
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Clinical features of arthritis related to hepatitis B virus (HBV) infection include the following:

  • Symmetric arthritis may be migratory or additive; with the hand and knee joints most commonly affected; significant morning stiffness and fusiform swelling are associated with HBV-induced arthritis

  • Arthritis and urticaria may precede jaundice by days to weeks and may persist for several weeks after jaundice resolves

  • Recurrent polyarthralgia or polyarthritis can occur in patients with chronic active hepatitis or chronic HBV viremia

  • Polyarteritis nodosa may be associated with chronic HBV viremia

  • Patients may have arthritis-dermatitis syndrome

  • Nephropathy has been described

  • Systemic necrotizing vasculitis is also a clinical feature

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