Which viruses are less common causes of viral arthritis?

Updated: Nov 12, 2019
  • Author: Rabea Ahmed Khouqeer, MD, FRCPC, FAAAAI; Chief Editor: Herbert S Diamond, MD  more...
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A number of other viruses have also been found to be capable of causing arthritis, including the following:

  • Epstein-Barr virus – This infection is usually associated with polyarthralgia, but monoarthritis of the knee and ruptured Baker cysts may occur

  • Varicella-zoster virus (VZV) – This infection in children rarely develops into pauciarticular arthritis [11]

  • Mumps virus – In infected adults, this infection is associated with small or large joint synovitis that lasts for several weeks; arthritis may precede or follow parotitis by up to 4 weeks

  • Adenovirus or coxsackieviruses A9, B2, B3, B4, and B6 – These infections have been associated with recurrent episodes of polyarthritis, pleuritis, myalgia, rash, pharyngitis, myocarditis, and leukocytosis

  • Echovirus - This infection can be associated with polyarthritis, fever, and myalgias

  • Herpes simplex virus (HSV) or cytomegalovirus (CMV) – Arthritis with these infections is rare; CMV arthritis has been reported in patients after bone marrow transplantation; vaccinia virus has been associated with postvaccination knee arthritis in only 2 reported cases

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