What is included in supportive care for amyloidosis?

Updated: May 09, 2019
  • Author: Robert O Holmes, Jr, DO; Chief Editor: Herbert S Diamond, MD  more...
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Answer

Answer

Very gentle afterload reduction with diuretics is important to decrease the effects of restrictive pathology and higher filling pressures, but orthostasis is common and dangerous. Attempting to make peripheral edema resolve with diuretics is not advised and can cause dangerously low cardiac output. If the patient has low and labile blood pressure that is thought to be related to autonomic dysfunction, midodrine, an alpha agonist, may improve blood pressure. [113]

Defibrillators may be a life-saving option for fatal arrhythmias, but there are no strong data indicating they prevent mortality. [115] Even so, pacemakers may still have a role in preventing symptomatic bradycardia or conduction blocks. [116]


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