Which immunocytochemical studies are performed in the diagnosis of amyloidosis?

Updated: May 09, 2019
  • Author: Robert O Holmes, Jr, DO; Chief Editor: Herbert S Diamond, MD  more...
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Answer

Answer

Immunocytochemical studies for amyloid should include the following [78] :

  • Stains for Congo red (apple-green birefringence)
  • Hematoxylin and eosin stains for amorphous material
  • Kappa and lambda light chains
  • Beta-amyloid A4 protein,
  • Transthyretin
  • Beta 2-microglobulin
  • Cystatin C
  • Gelsolin
  • Immunoreactivity with antiamyloid AA antibody

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