Is sulfasalazine (SSZ) safe for breastfeeding women with rheumatoid arthritis (RA)?

Updated: May 11, 2018
  • Author: Katherine K Temprano, MD; Chief Editor: Christine Isaacs, MD  more...
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Answer

Answer

Only negligible amounts of SSZ were found to transfer into breast milk. [55] SSZ is believed to be safe during nursing, although the American Academy of Pediatrics has cited a reported case of bloody diarrhea in an infant as a reason to use caution with this drug during nursing. [56]

Both EULAR and BSR-BHPR guidelines find SSZ compatible with breastfeeding in healthy, full-term infants. [18, 19]


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