What is the role of amputation in the treatment of complex regional pain syndrome type 1 (CRPS 1) (RSD)?

Updated: Sep 09, 2018
  • Author: T P Sudha Rao, MD; Chief Editor: Herbert S Diamond, MD  more...
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Answer

Amputation is sometimes performed in patients with severe complications of CRPS type 1 who have severe, untreatable inflammation with the threat of sepsis or severe functional impairment. Patients who are in despair may request amputation as a last resort. [24, 20]

Two evidence-based guidelines found insufficient evidence that amputation makes a positive contribution to the treatment of CRPS 1. [24, 20] A more recent study that compared pain, function, depression, and quality of life in 19 patients with intractable CRPS who underwent amputation, and 19 patients in whom amputation was considered but not performed, reported consistently better results in the amputation group and recommended considering amputation for patients with intractable CRPS. [25]


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