What is the role of lab tests in the workup of nonarticular rheumatism/regional pain syndromes?

Updated: Apr 04, 2018
  • Author: T P Sudha Rao, MD; Chief Editor: Herbert S Diamond, MD  more...
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Obtain the following studies to screen for systemic disease. All should yield results within the reference range.

  • Complete blood cell count (CBC)

  • Erythrocyte sedimentation rate (ESR)

  • Thyroid-stimulating hormone (TSH)

  • Electrolytes, calcium, alanine aminotransferase (ALT), creatinine

If indicated by history findings or abnormalities found on physical examination, the following studies may be obtained. All should yield results within the reference range unless the patient has a coexistent systemic illness:

  • Antinuclear antibody (ANA) for systemic autoimmune disease (Many false-positive tests have been reported.)

  • Rheumatoid factor (RF) for rheumatoid arthritis or immune complex disease

  • Creatine kinase (CK) for myositis

  • HIV serology

  • Lyme serology for Lyme disease (enzyme-linked immunosorbent assay [ELISA] screen and, if positive, Western blot to confirm)

  • Prolactin for panhypopituitarism

  • Urinalysis for renal disease

  • Hepatitis C antibody

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