Which infections may cause leukocytoclastic vasculitis (LCV)?

Updated: Dec 09, 2020
  • Author: A Brooke W Eastham, MD; Chief Editor: Herbert S Diamond, MD  more...
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Answer

Infections that may be associated with vasculitis include the following:

  • Upper respiratory tract infections, particularly with beta-hemolytic streptococci, and viral hepatitis are implicated most often

  • HIV infection is also associated with some cases of LCV; in addtion, LCV has been posited as an immune reconstitution inflammatory syndrome (IRIS) related to antiretroviral treatment for HIV infection [22]

  • Leukocytoclastic vasculitis may be seen with bacterial endocarditis

  • Hepatitis C is a commonly recognized cause of LCV, likely through the presence of cryoglobulins. [23]


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