What is the role of nucleic acid amplification tests (NAATs) in the diagnosis of gonococcal arthritis?

Updated: Jan 12, 2019
  • Author: Victoria Fernandes Sullivan, MD; Chief Editor: Herbert S Diamond, MD  more...
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Nucleic acid amplification tests (NAATs) may be used as an adjunct to cultures and can be performed on samples from the cervix, urethra, rectum, urine, pharynx, synovial fluid, [14] and skin. [15] These tests can help to confirm a diagnosis of DGI when cultures are negative. [14, 15, 16] However, an important limitation of polymerase chain reaction (PCR) and other NAATs is they do not provide antibiotic sensitivities to guide choice of antibiotic for treatment.

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