Which medications in the drug class Cytotoxic agents are used in the treatment of Eosinophilic Granulomatosis with Polyangiitis (Churg-Strauss Syndrome)?

Updated: Dec 24, 2018
  • Author: Spencer T Lowe, MD; Chief Editor: Herbert S Diamond, MD  more...
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Answer

Cytotoxic agents

These agents inhibit cell growth and proliferation. They are reserved for cases resistant to corticosteroids.

Cyclophosphamide (Cytoxan, Neosar)

Chemically related to nitrogen mustards. As an alkylating agent, the mechanism of action of the active metabolites may involve cross-linking of DNA, which interferes with growth of rapidly proliferating cells.


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